Compile Data Set for Download or QSAR
Found 9 of ki data for polymerid = 1896,1899,50001395
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))TBA
LigandPNGBDBM50614449(CHEMBL1163086)copy SMILES
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails
TargetGlutamate--tRNA ligase(Escherichia coli)
CREFSIP

LigandPNGBDBM18122((4S)-4-amino-5-[({[(2R,3S,4R,5R)-5-(6-amino-9H-pur...)copy SMILEScopy InChI
Affinity DataKi:  2.80nM ΔG°:  -50.8kJ/molepH: 7.2 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X0659CPubMed
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))TBA
LigandPNGBDBM50097096(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)copy SMILEScopy InChI
Affinity DataKi:  5.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))TBA
LigandPNGBDBM50097096(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q23ZH8PubMed
TargetProbable glutamate--tRNA ligase, mitochondrial(Mus musculus (mouse))
CREFSIP

LigandPNGBDBM18122((4S)-4-amino-5-[({[(2R,3S,4R,5R)-5-(6-amino-9H-pur...)copy SMILEScopy InChI
Affinity DataKi:  70nM ΔG°:  -41.5kJ/molepH: 8.0 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X0659CPubMed
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))TBA
LigandPNGBDBM50614450(CHEMBL5279127)copy SMILES
Affinity DataKi:  85nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutamate--tRNA ligase(Escherichia coli)
CREFSIP

LigandPNGBDBM18123((5S)-5-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nM ΔG°:  -28.6kJ/molepH: 7.2 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X0659CPubMed
TargetGlutamate--tRNA ligase(Escherichia coli)
CREFSIP

LigandPNGBDBM18118((4S)-4-amino-6-({[(2R,3S,4R,5R)-5-(6-amino-9H-puri...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nM ΔG°:  -28.2kJ/molepH: 7.2 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZD3PubMed
TargetGlutamate--tRNA ligase(Escherichia coli)
CREFSIP

LigandPNGBDBM18120(Gln-KPA | [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+6nM ΔG°:  -15.1kJ/molepH: 7.2 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N7ZD3PubMed