Compile Data Set for Download or QSAR
Found 4435 of ki data for polymerid = 49000889,49000994,49000996
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50398057(CHEMBL2181924)copy SMILEScopy InChI
Affinity DataKi:  0.00250nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50170654((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.0100nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639QHBPubMed
LigandPNGBDBM50170654((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.0110nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR208CPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50146585(CHEMBL3763396)copy SMILEScopy InChI
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50145021(1-Cyclohexyl-4-[4-(1,2,3,4-tetrahydro-naphthalen-1...)copy SMILEScopy InChI
Affinity DataKi:  0.0360nMAssay Description:In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN44HSPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50170652((2R,6S)-2,6-Dimethyl-4-tridecyl-morpholine | CHEMB...)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639QHBPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50038707(1-(4-Nitro-phenyl)-cyclopentanecarboxylic acid 2-(...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Affinity at sigma-1 site by inhibition of [3H](+)-pentazocine (PENT) binding in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ2BMRPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50038707(1-(4-Nitro-phenyl)-cyclopentanecarboxylic acid 2-(...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Affinity at sigma-1 site by inhibition of [3H](+)-pentazocine (PENT) binding in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ2BMRPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50415166(CHEMBL578825)copy SMILEScopy InChI
Affinity DataKi:  0.0525nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B9SPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50415165(CHEMBL570795)copy SMILEScopy InChI
Affinity DataKi:  0.0575nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B9SPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50415164(CHEMBL570529)copy SMILEScopy InChI
Affinity DataKi:  0.0661nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B9SPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50144508(4-Methyl-1-(5-phenyl-pentyl)-piperidine | CHEMBL30...)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R210T8PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50251208(CHEMBL4088272)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50170654((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor expressed in Saccharomyces cerevisiae WA0More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4VZTPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50415163(CHEMBL571418)copy SMILEScopy InChI
Affinity DataKi:  0.0891nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B9SPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50144518(1-(5,5-Diphenyl-pentyl)-4-methyl-piperidine | CHEM...)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R210T8PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50415162(CHEMBL572294)copy SMILEScopy InChI
Affinity DataKi:  0.0977nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B9SPubMed
LigandPNGBDBM50248926(3-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)benzo[...)copy SMILEScopy InChI
Affinity DataKi:  0.0980nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR208CPubMed
LigandPNGBDBM50248926(3-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)benzo[...)copy SMILEScopy InChI
Affinity DataKi:  0.0980nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat liver membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP4712PubMed
LigandPNGBDBM50248926(3-((1-(4-chlorobenzyl)piperidin-4-yl)methyl)benzo[...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat liver membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639PHXPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50415161(CHEMBL570067)copy SMILEScopy InChI
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B9SPubMed
LigandPNGBDBM50007410(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969B5PubMed
LigandPNGBDBM50374600(CHEMBL272899)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H](+)-pentazocine from opioid sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736RTZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50144512(1-(5,5-Diphenyl-pent-4-enyl)-4-methyl-piperidine |...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R210T8PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50065136(CHEMBL81455 | N-(2-Azepan-1-yl-ethyl)-4-iodo-N-met...)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Inhibition of [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8XHMPubMed
LigandPNGBDBM50494706(CHEMBL3093268)copy SMILEScopy InChI
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969B5PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50041259(CHEMBL19355 | Phenethyl-(5-phenyl-pentyl)-amine)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R210T8PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50041259(CHEMBL19355 | Phenethyl-(5-phenyl-pentyl)-amine)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30QVPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50000066((2-Azepan-1-yl-ethyl)-[2-(3,4-dichloro-phenyl)-eth...)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP01RWPubMed
LigandPNGBDBM50000066((2-Azepan-1-yl-ethyl)-[2-(3,4-dichloro-phenyl)-eth...)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Inhibition of [3H]-NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6CW7PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50065134(CHEMBL309983 | N-(2-Azepan-1-yl-ethyl)-4-bromo-N-m...)copy SMILEScopy InChI
Affinity DataKi:  0.180nMAssay Description:Inhibition of [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8XHMPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50041268(Benzyl-methyl-(5-phenyl-pentyl)-amine | CHEMBL1931...)copy SMILEScopy InChI
Affinity DataKi:  0.190nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30QVPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50170636(2-[4-(3-Dibenzo[b,f]azepin-5-yl-propyl)-piperazin-...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639QHBPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50415160(CHEMBL571659)copy SMILEScopy InChI
Affinity DataKi:  0.209nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B9SPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50145029(1-Cyclohexyl-4-(4-naphthalen-1-yl-butyl)-piperazin...)copy SMILEScopy InChI
Affinity DataKi:  0.220nMAssay Description:In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN44HSPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50041246(CHEMBL19544 | Methyl-phenethyl-(5-phenyl-pentyl)-a...)copy SMILEScopy InChI
Affinity DataKi:  0.25nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30QVPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50041246(CHEMBL19544 | Methyl-phenethyl-(5-phenyl-pentyl)-a...)copy SMILEScopy InChI
Affinity DataKi:  0.25nMAssay Description:Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R210T8PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50041277((5-Cyclohexyl-pentyl)-dimethyl-amine | CHEMBL20036)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30QVPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50000068(CHEMBL142700 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP01RWPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50038717(1-(4-Nitro-phenyl)-cyclopentanecarboxylic acid 3-(...)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Affinity at sigma-1 site by inhibition of [3H](+)-pentazocine (PENT) binding in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ2BMRPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50041257((5-Phenyl-pentyl)-(3-phenyl-propyl)-amine | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30QVPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50041275(CHEMBL20348 | Methyl-(5-phenyl-pentyl)-propyl-amin...)copy SMILEScopy InChI
Affinity DataKi:  0.290nMAssay Description:Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30QVPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50037480((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...)copy SMILEScopy InChI
Affinity DataKi:  0.290nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24B31ZDPubMed
LigandPNGBDBM50532486(CHEMBL4564992)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93C14PubMed
LigandPNGBDBM50532486(CHEMBL4564992)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93C14PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50159021(1-Benzyl-4-chroman-3-ylmethyl-piperazine | 1-benzy...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3MZWPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50159018(1-Benzyl-4-chroman-2-ylmethyl-piperazine | 1-benzy...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3MZWPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50159013(3-(4-Benzyl-piperazin-1-ylmethyl)-3,4-dihydro-2H-n...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3MZWPubMed
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