Found 112 hits of Enzyme Inhibition Constant Data
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 90.4nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 96.4nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 97.9nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 99.4nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of rat 5HT2 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H](-)CGP12177 from human recombinant beta-1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT5A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]U69593 from guinea pig cerebellum kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]SCH23390 from human recombinant dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]APT from human recombinant histamine H2 receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]4-DAMP from human recombinant muscarinic M3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptorMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]BTCP from human recombinant DATMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]AB-MECA from human recombinant adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]spiperone from human recombinant dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pirenzepine from human recombinant muscarinic M1 receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]AF-DX384 from human recombinant muscarinic M2 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
ASKA Pharmaceutical Co, Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]peptide YY from NPY2 receptor in human KAN-TS cellsMore data for this Ligand-Target Pair