Compile Data Set for Download or QSAR

Found 81 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337610(CHEMBL1683065 | trans-((1S,3R)-3-(3-ethyl-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337617(CHEMBL1683072 | cis-((1S,3R)-1-isopropyl-3-(3-(met...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337624(((1S,3R)-1-sec-butyl-3-((3S,4S)-3-methoxy-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337615(CHEMBL1683070 | cis-((1S,3R)-3-(3-ethoxy-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337625(((1R,3R)-1-(cyclopropylmethyl)-3-((3S,4S)-3-methox...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Mus musculus)
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Binding affinity to mouse CCR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337604(CHEMBL1683059 | Cis-((1S,3R)-1-isopropyl-3-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337618(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337605(CHEMBL1683060 | Cis-((1S,3R)-1-isopropyl-3-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337628(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337607(CHEMBL1683062 | trans-((1S,3R)-1-isopropyl-3-(3-me...)copy SMILEScopy InChI
Affinity DataIC50: 175nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337616(CHEMBL1683071 | cis-((1S,3R)-1-isopropyl-3-(3-(met...)copy SMILEScopy InChI
Affinity DataIC50: 201nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337613(CHEMBL1683068 | cis-((1S,3R)-1-isopropyl-3-(3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 204nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337615(CHEMBL1683070 | cis-((1S,3R)-3-(3-ethoxy-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337603((4-(3,5-bis(trifluoromethyl)phenyl)piperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 213nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337621(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)copy SMILEScopy InChI
Affinity DataIC50: 221nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337629(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)copy SMILEScopy InChI
Affinity DataIC50: 232nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337602(((1S,3R)-1-isopropyl-3-(tetrahydro-2H-pyran-4-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 283nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337630(((1R,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)copy SMILEScopy InChI
Affinity DataIC50: 294nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337609(CHEMBL1683064 | cis-((1S,3R)-3-(3-ethyl-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 312nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337606(CHEMBL1683061 | trans-((1S,3R)-1-isopropyl-3-(3-me...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337611(CHEMBL1683066 | trans-((1S,3R)-3-(3-ethyl-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 462nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337610(CHEMBL1683065 | trans-((1S,3R)-3-(3-ethyl-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 546nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337617(CHEMBL1683072 | cis-((1S,3R)-1-isopropyl-3-(3-(met...)copy SMILEScopy InChI
Affinity DataIC50: 572nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337600(((1S,3R)-1-isopropyl-3-(tetrahydro-2H-pyran-4-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 904nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337611(CHEMBL1683066 | trans-((1S,3R)-3-(3-ethyl-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337607(CHEMBL1683062 | trans-((1S,3R)-1-isopropyl-3-(3-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337631(((1S,3R)-1-(2-hydroxypropan-2-yl)-3-((3S,4S)-3-met...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
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