Compile Data Set for Download or QSAR

Found 120 hits of Enzyme Inhibition Constant Data   

TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341099(2-(2-(4-(3-(4-chlorophenyl)-1H-pyrazole-5-carbonyl...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341079((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341076((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyb...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341105((4-(2-methoxyphenyl)piperazin-1-yl)(3-(4-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341075((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341093((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-ethylphe...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341080((3-(4-chlorophenyl)-1-methyl-1H-pyrazol-5-yl)(4-(2...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341081((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341078((S)-(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-meth...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341109((3-(2,4-dichlorophenyl)-1H-pyrazol-5-yl)(4-(2-meth...)copy SMILEScopy InChI
Affinity DataIC50: 205nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341108(4-(5-(4-(2-methoxyphenyl)piperazine-1-carbonyl)-1H...)copy SMILEScopy InChI
Affinity DataIC50: 208nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341103((3-(4-fluorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341082((5-(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)(4-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341097((4-(5-chloro-2-methoxyphenyl)piperazin-1-yl)(3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341106((4-(2-methoxyphenyl)piperazin-1-yl)(3-p-tolyl-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341094(2-(4-(3-(4-chlorophenyl)-1H-pyrazole-5-carbonyl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341074((4-(2-methoxyphenyl)piperazin-1-yl)(3-phenyl-1H-py...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341102((3-(3-fluorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50291261((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341083((5-(4-chlorophenyl)isoxazol-3-yl)(4-(2-methoxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341101((3-(2-fluorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341095((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-hydroxyp...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341086((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(pyridin-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341077((3-cyclohexyl-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50051293((S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinol...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341073((3-phenyl-1H-pyrazol-5-yl)(4-phenylpiperazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341107((4-(2-methoxyphenyl)piperazin-1-yl)(3-(4-(methylsu...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341115((R)-(3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341080((3-(4-chlorophenyl)-1-methyl-1H-pyrazol-5-yl)(4-(2...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341075((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341075((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341113(4-(3-(4-chlorophenyl)-1H-pyrazole-5-carbonyl)-1-(2...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341110((4-(2-methoxyphenyl)piperazin-1-yl)(3-(pyridin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341100((3-benzyl-1H-pyrazol-5-yl)(4-(2-methoxyphenyl)pipe...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341085((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(pyridin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.81E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341081((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50051293((S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinol...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50051293((S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinol...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341116((4-(2-methoxyphenyl)piperazin-1-yl)(3-phenylisoxaz...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341084((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 5.09E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341080((3-(4-chlorophenyl)-1-methyl-1H-pyrazol-5-yl)(4-(2...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50291261((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341111((4-(2-methoxyphenyl)piperazin-1-yl)(3-(pyridin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341112((4-(2-methoxyphenyl)piperazin-1-yl)(3-(pyridin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341114(1-(2-methoxyphenyl)-4-(3-phenyl-1H-pyrazol-5-ylsul...)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341075((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(2-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341081((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50051293((S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinol...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341089((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-(4-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341091((3-(4-chlorophenyl)-1H-pyrazol-5-yl)(4-o-tolylpipe...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56K16PubMed
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