Compile Data Set for Download or QSAR

Found 115 hits of Enzyme Inhibition Constant Data   

TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352410(CHEMBL1823855)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352398(CHEMBL1823843)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352422(CHEMBL1823616)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352447(CHEMBL1823580)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352413(CHEMBL1823858)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352429(CHEMBL1823588)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352409(CHEMBL1823854)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetTranscriptional regulator ERG(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352421(CHEMBL1823591)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352425(CHEMBL1823581)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352421(CHEMBL1823591)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352421(CHEMBL1823591)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352421(CHEMBL1823591)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetTranscriptional regulator ERG(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352296(CHEMBL1822468)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetTranscriptional regulator ERG(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352420(CHEMBL1823865)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetTranscriptional regulator ERG(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352422(CHEMBL1823616)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
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