Compile Data Set for Download or QSAR

Found 210 hits of Enzyme Inhibition Constant Data   

LigandPNGBDBM50393347(CHEMBL2152138)copy SMILEScopy InChI
Affinity DataIC50: 2.96E+3nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393337(CHEMBL2152129)copy SMILEScopy InChI
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393344(CHEMBL2152135)copy SMILEScopy InChI
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393347(CHEMBL2152138)copy SMILEScopy InChI
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393346(CHEMBL2152137)copy SMILEScopy InChI
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393335(CHEMBL2152127)copy SMILEScopy InChI
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393336(CHEMBL2152128)copy SMILEScopy InChI
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetInsulin receptor(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CDC7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetAurora kinase B(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Aurora kinase BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetInsulin receptor(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CDK1/CyclinBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Platelet-derived growth factor subunit BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CDK1/CyclinBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetAurora kinase B(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Aurora kinase BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Platelet-derived growth factor subunit BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CDC7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393331(CHEMBL2152124)copy SMILEScopy InChI
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
LigandPNGBDBM50393346(CHEMBL2152137)copy SMILEScopy InChI
Affinity DataIC50: 3.64E+3nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393332(CHEMBL2152125)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393362(CHEMBL2152254)copy SMILEScopy InChI
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393358(CHEMBL2152149)copy SMILEScopy InChI
Affinity DataIC50: 4.44E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393362(CHEMBL2152254)copy SMILEScopy InChI
Affinity DataIC50: 4.65E+3nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393356(CHEMBL2152147)copy SMILEScopy InChI
Affinity DataIC50: 4.77E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393361(CHEMBL2152251)copy SMILEScopy InChI
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393352(CHEMBL2152143)copy SMILEScopy InChI
Affinity DataIC50: 5.07E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393336(CHEMBL2152128)copy SMILEScopy InChI
Affinity DataIC50: 5.43E+3nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393332(CHEMBL2152125)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393362(CHEMBL2152254)copy SMILEScopy InChI
Affinity DataIC50: 6.28E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393347(CHEMBL2152138)copy SMILEScopy InChI
Affinity DataIC50: 6.34E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393336(CHEMBL2152128)copy SMILEScopy InChI
Affinity DataIC50: 8.36E+3nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393332(CHEMBL2152125)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
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