Compile Data Set for Download or QSAR

Found 210 hits of Enzyme Inhibition Constant Data   

LigandPNGBDBM50393353(CHEMBL2152144)copy SMILEScopy InChI
Affinity DataIC50: 184nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393345(CHEMBL2152136)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:Inhibition of CRAF1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393357(CHEMBL2152148)copy SMILEScopy InChI
Affinity DataIC50: 209nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393335(CHEMBL2152127)copy SMILEScopy InChI
Affinity DataIC50: 213nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393335(CHEMBL2152127)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393364(CHEMBL2152256)copy SMILEScopy InChI
Affinity DataIC50: 234nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393333(CHEMBL2151050)copy SMILEScopy InChI
Affinity DataIC50: 264nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393351(CHEMBL2152142)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)copy SMILEScopy InChI
Affinity DataIC50: 298nMAssay Description:Inhibition of human PI3Kgamma expressed in sf9 cells assessed as amount of ATP consumed by luciferase-luciferin chemiluminescence assayMore data for this Ligand-Target Pair
LigandPNGBDBM50393350(CHEMBL2152141)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393359(CHEMBL2152150)copy SMILEScopy InChI
Affinity DataIC50: 323nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393349(CHEMBL2152140)copy SMILEScopy InChI
Affinity DataIC50: 323nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393337(CHEMBL2152129)copy SMILEScopy InChI
Affinity DataIC50: 326nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393357(CHEMBL2152148)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 342nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393338(CHEMBL2152130)copy SMILEScopy InChI
Affinity DataIC50: 352nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393345(CHEMBL2152136)copy SMILEScopy InChI
Affinity DataIC50: 362nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393333(CHEMBL2151050)copy SMILEScopy InChI
Affinity DataIC50: 387nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393355(CHEMBL2152146)copy SMILEScopy InChI
Affinity DataIC50: 394nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393356(CHEMBL2152147)copy SMILEScopy InChI
Affinity DataIC50: 409nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393350(CHEMBL2152141)copy SMILEScopy InChI
Affinity DataIC50: 415nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393329(CHEMBL2152253)copy SMILEScopy InChI
Affinity DataIC50: 415nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393351(CHEMBL2152142)copy SMILEScopy InChI
Affinity DataIC50: 431nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 435nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393353(CHEMBL2152144)copy SMILEScopy InChI
Affinity DataIC50: 437nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393331(CHEMBL2152124)copy SMILEScopy InChI
Affinity DataIC50: 441nMAssay Description:Inhibition of human PI3Kgamma expressed in sf9 cells assessed as amount of ATP consumed by luciferase-luciferin chemiluminescence assayMore data for this Ligand-Target Pair
LigandPNGBDBM50393335(CHEMBL2152127)copy SMILEScopy InChI
Affinity DataIC50: 456nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393359(CHEMBL2152150)copy SMILEScopy InChI
Affinity DataIC50: 464nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393354(CHEMBL2152145)copy SMILEScopy InChI
Affinity DataIC50: 476nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393362(CHEMBL2152254)copy SMILEScopy InChI
Affinity DataIC50: 497nMAssay Description:Inhibition of human PI3Kgamma expressed in sf9 cells assessed as amount of ATP consumed by luciferase-luciferin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393334(CHEMBL2152126)copy SMILEScopy InChI
Affinity DataIC50: 505nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393343(CHEMBL2152134)copy SMILEScopy InChI
Affinity DataIC50: 507nMAssay Description:Inhibition of human PI3Kgamma expressed in sf9 cells assessed as amount of ATP consumed by luciferase-luciferin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393354(CHEMBL2152145)copy SMILEScopy InChI
Affinity DataIC50: 507nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393357(CHEMBL2152148)copy SMILEScopy InChI
Affinity DataIC50: 528nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393332(CHEMBL2152125)copy SMILEScopy InChI
Affinity DataIC50: 529nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393345(CHEMBL2152136)copy SMILEScopy InChI
Affinity DataIC50: 533nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393355(CHEMBL2152146)copy SMILEScopy InChI
Affinity DataIC50: 539nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393351(CHEMBL2152142)copy SMILEScopy InChI
Affinity DataIC50: 546nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393352(CHEMBL2152143)copy SMILEScopy InChI
Affinity DataIC50: 552nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393360(CHEMBL2152250)copy SMILEScopy InChI
Affinity DataIC50: 555nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393349(CHEMBL2152140)copy SMILEScopy InChI
Affinity DataIC50: 568nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393349(CHEMBL2152140)copy SMILEScopy InChI
Affinity DataIC50: 572nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393338(CHEMBL2152130)copy SMILEScopy InChI
Affinity DataIC50: 578nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393360(CHEMBL2152250)copy SMILEScopy InChI
Affinity DataIC50: 587nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 591nMAssay Description:Inhibition of human CYP2C9 using tolbutamide as substrate after 15 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 623nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393340(CHEMBL2152132)copy SMILEScopy InChI
Affinity DataIC50: 638nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393342(CHEMBL2152252)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
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