Compile Data Set for Download or QSAR

Found 64 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121382(CHEMBL3622131)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121390(CHEMBL3622138)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation after 72 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121382(CHEMBL3622131)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetDeath-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant DAPK1 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121381(CHEMBL3622132)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121381(CHEMBL3622132)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant Tyk2 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant LCK (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121382(CHEMBL3622131)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant Src (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121381(CHEMBL3622132)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121389(CHEMBL3622139)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121387(CHEMBL3622141)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of recombinant JAK3 (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research& Development

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)copy SMILEScopy InChI
Affinity DataEC50: >1.60E+4nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q2421MPubMed
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