Found 123 hits of Enzyme Inhibition Constant Data
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataKi: 610nMAssay Description:Inhibition of PIM2 kinase (unknown origin) using Biotin-AGAGRSRHSSYPAGT-OH as substrate after 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of PKCtheta (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase N1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of PKN1 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of VPS34 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of PI4Kbeta (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKBalpha (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PAK2 (unknown origin)More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDK1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MNK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CAMK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKCalpha (unknown origin)More data for this Ligand-Target Pair
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RON (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MK5 (unknown origin)More data for this Ligand-Target Pair
TargetEphrin type-A receptor 4(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHA4 (unknown origin)More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 12(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38gamma (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase WNK1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of WNK1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FYN (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MNK2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-A1/Cyclin-dependent kinase 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CSK (unknown origin)More data for this Ligand-Target Pair
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHB4 (unknown origin)More data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MK2 (unknown origin)More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
