Found 112 hits of Enzyme Inhibition Constant Data   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512296(CHEMBL4445755)copy SMILEScopy InChI

Affinity DataIC50: 540nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512308(CHEMBL4474475)copy SMILEScopy InChI

Affinity DataIC50: 572nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512308(CHEMBL4474475)copy SMILEScopy InChI

Affinity DataIC50: 597nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512298(CHEMBL4583776)copy SMILEScopy InChI

Affinity DataIC50: 719nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512295(CHEMBL4447337)copy SMILEScopy InChI

Affinity DataIC50: 790nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as reduction in antihuman IgE antibody-stimulated CD63 expression preincubated for 30 mins foll...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMedPDB
3D Structure (crystal)

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512294(CHEMBL4550818)copy SMILEScopy InChI

Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512295(CHEMBL4447337)copy SMILEScopy InChI

Affinity DataIC50: 810nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as reduction in anti-CD79b antibody-induced CD69 expression preincubated for 60 mins followed b...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMedPDB
3D Structure (crystal)

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512306(CHEMBL4528393)copy SMILEScopy InChI

Affinity DataIC50: 904nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512297(CHEMBL4435158)copy SMILEScopy InChI

Affinity DataIC50: 970nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512295(CHEMBL4447337)copy SMILEScopy InChI

Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of PDE3 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512314(CHEMBL4591038)copy SMILEScopy InChI

Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512304(CHEMBL4454569)copy SMILEScopy InChI

Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512295(CHEMBL4447337)copy SMILEScopy InChI

Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512294(CHEMBL4550818)copy SMILEScopy InChI

Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512312(CHEMBL4522133)copy SMILEScopy InChI

Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512312(CHEMBL4522133)copy SMILEScopy InChI

Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512299(CHEMBL4589857)copy SMILEScopy InChI

Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512314(CHEMBL4591038)copy SMILEScopy InChI

Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512299(CHEMBL4589857)copy SMILEScopy InChI

Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512306(CHEMBL4528393)copy SMILEScopy InChI

Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512295(CHEMBL4447337)copy SMILEScopy InChI

Affinity DataIC50: 2.35E+3nMAssay Description:Inhibition of PDE1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512311(CHEMBL4483370)copy SMILEScopy InChI

Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512297(CHEMBL4435158)copy SMILEScopy InChI

Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512295(CHEMBL4447337)copy SMILEScopy InChI

Affinity DataIC50: 4.01E+3nMAssay Description:Inhibition of PDE10 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512295(CHEMBL4447337)copy SMILEScopy InChI

Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512299(CHEMBL4589857)copy SMILEScopy InChI

Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM334245((3-((8-(1-ethyl-5-methyl-1H- pyrazol-4-yl)-9-methy...)copy SMILEScopy InChI

Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI

Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512304(CHEMBL4454569)copy SMILEScopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM334245((3-((8-(1-ethyl-5-methyl-1H- pyrazol-4-yl)-9-methy...)copy SMILEScopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110alpha/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512301(CHEMBL4570812)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE11 (unknown origin)More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE11 (unknown origin)More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE3 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE10 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetO43924/P16499/P18545/P35913/P51160/Q13956(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE10 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE8 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE9 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE7 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE9 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE7 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetO43924/P16499/P18545/P35913/P51160/Q13956(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE6 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE3 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512300(CHEMBL4575012)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50512302(CHEMBL4441262)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PDE8 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98CDFPubMed