Compile Data Set for Download or QSAR

Found 314 hits of Enzyme Inhibition Constant Data   

TargetMAP kinase-activated protein kinase 3(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 2.54E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetMisshapen-like kinase 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 2.81E+4nMAssay Description:Inhibition of recombinant full length human His-tagged GSK3beta expressed in baculovirus expression system using serine/threonine-9 peptide as substr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 2.91E+4nMAssay Description:Inhibition of recombinant full length human His-tagged RSK2 expressed in baculovirus expression system using serine/threonine-6 peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of recombinant full length human GST-tagged KHS1 expressed in baculovirus expression system using serine/threonine-7 peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant human GST-tagged EPHA1 cytoplasmic domain (568 to 976 residues) expressed in baculovirus expression system using Tyr 02 as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetG protein-coupled receptor kinase 4(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibition of recombinant full length human GST-tagged GRK4 expressed in baculovirus expression system using serine/threonine-16 peptide as substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of full length recombinant GST-tagged human YES1 expressed in baculovirus expression system using tyr 02 peptide as substrate after 1 hr i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 3.76E+4nMAssay Description:Inhibition of recombinant human His-tagged KDR (789 to 1356 residues) expressed in baculovirus expression system using Tyr1 as substrate incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 3.76E+4nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HCK expressed in baculovirus expression system using Tyr 02 as substrate after 1 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of recombinant human GST-tagged EPHB1 catalytic domain expressed in baculovirus expression system using tyrosine-2 peptide as substrate in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 3.96E+4nMAssay Description:Inhibition of recombinant full length human His-tagged BTK expressed in baculovirus expression system using tyrosine-2 peptide as substrate incubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of recombinant GST-tagged human PIK3C2B catalytic domain expressed in baculovirus expression system using PI as substrate after 1 hr in pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetSerine/threonine-protein kinase D2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition Protein kinase C gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetPhosphatidylinositol 4-kinase alpha(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged AKT2 expressed in baculovirus expression system using Ser/Thr-06 peptide as substrate incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of neuraminidase of influenza A/PR/8/34(H1N1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetSRSF protein kinase 3(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of neuraminidase of influenza A/PR/8/34(H1N1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged PDGFRalpha D842V cytoplasmic domain expressed in baculovirus expression system using tyrosine-4 peptide as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His-tagged FGFR4 catalytic domain (781 to 1338 residues) expressed in baculovirus expression system using tyrosine-4 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human FYN cytoplasmic domain expressed in baculovirus expression system using fluorophore...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His-tagged IGF1R expressed in baculovirus expression system using tyrosine 1 peptide as substrate incubated for 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length His-tagged human IKKalpha expressed in baculovirus expression system after 1 hr in presence of ATP by Adapta as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged LCK expressed in baculovirus expression system using tyrosine-2 peptide as substrate incubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged MEK2 expressed in baculovirus expression system using serine/threonine-3 peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetDual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged MAP2K6 expressed in baculovirus expression system using serine/threonine-3 peptide as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetMAP/microtubule affinity-regulating kinase 3(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human GST-tagged MARK3 expressed in baculovirus expression system using serine/threonine-25 peptide as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged PIM1 expressed in baculovirus expression system using serine/threonine-7 peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged TIE2 (817 to 1101 residues) expressed in baculovirus expression system using tyrosine-5 peptide as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetSerine/threonine-protein kinase 24(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human GST-tagged MST3 expressed in baculovirus expression system using serine/threonine-7 peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus expression system using tyrosine...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using tyrosine-2 peptide as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetSerine/threonine-protein kinase N1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length GST-tagged human PKN1 expressed in baculovirus expression system using Ser/Thr 07 as substrate in presence of A...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged ROCK1 catalytic domain expressed in baculovirus expression system using serine/threonine-7 peptide as subs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PIK3C2alpha catalytic domain expressed in baculovirus expression system using PI li...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged TYK2 catalytic domain (833 to 1187 residues) expressed in baculovirus expression system using tyrosine-3 p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged PDGFRalpha V561D mutant cytoplasmic domain expressed in baculovirus expression system using tyrosine-4 pep...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
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