Found 314 hits of Enzyme Inhibition Constant Data
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
Affinity DataIC50: 2.54E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
Affinity DataIC50: 2.81E+4nMAssay Description:Inhibition of recombinant full length human His-tagged GSK3beta expressed in baculovirus expression system using serine/threonine-9 peptide as substr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.91E+4nMAssay Description:Inhibition of recombinant full length human His-tagged RSK2 expressed in baculovirus expression system using serine/threonine-6 peptide as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of recombinant full length human GST-tagged KHS1 expressed in baculovirus expression system using serine/threonine-7 peptide as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant human GST-tagged EPHA1 cytoplasmic domain (568 to 976 residues) expressed in baculovirus expression system using Tyr 02 as ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibition of recombinant full length human GST-tagged GRK4 expressed in baculovirus expression system using serine/threonine-16 peptide as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of full length recombinant GST-tagged human YES1 expressed in baculovirus expression system using tyr 02 peptide as substrate after 1 hr i...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 3.76E+4nMAssay Description:Inhibition of recombinant human His-tagged KDR (789 to 1356 residues) expressed in baculovirus expression system using Tyr1 as substrate incubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 3.76E+4nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HCK expressed in baculovirus expression system using Tyr 02 as substrate after 1 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of recombinant human GST-tagged EPHB1 catalytic domain expressed in baculovirus expression system using tyrosine-2 peptide as substrate in...More data for this Ligand-Target Pair
Affinity DataIC50: 3.96E+4nMAssay Description:Inhibition of recombinant full length human His-tagged BTK expressed in baculovirus expression system using tyrosine-2 peptide as substrate incubated...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of recombinant GST-tagged human PIK3C2B catalytic domain expressed in baculovirus expression system using PI as substrate after 1 hr in pr...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition Protein kinase C gammaMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of the fibroblast growth factor receptor (FGFR1)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against cytosolic c-SrcMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged AKT2 expressed in baculovirus expression system using Ser/Thr-06 peptide as substrate incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of neuraminidase of influenza A/PR/8/34(H1N1)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of neuraminidase of influenza A/PR/8/34(H1N1)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged PDGFRalpha D842V cytoplasmic domain expressed in baculovirus expression system using tyrosine-4 peptide as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His-tagged FGFR4 catalytic domain (781 to 1338 residues) expressed in baculovirus expression system using tyrosine-4 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human FYN cytoplasmic domain expressed in baculovirus expression system using fluorophore...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human His-tagged IGF1R expressed in baculovirus expression system using tyrosine 1 peptide as substrate incubated for 60 mi...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length His-tagged human IKKalpha expressed in baculovirus expression system after 1 hr in presence of ATP by Adapta as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged LCK expressed in baculovirus expression system using tyrosine-2 peptide as substrate incubated...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged MEK2 expressed in baculovirus expression system using serine/threonine-3 peptide as substrate ...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged MAP2K6 expressed in baculovirus expression system using serine/threonine-3 peptide as substrat...More data for this Ligand-Target Pair
TargetMAP/microtubule affinity-regulating kinase 3(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human GST-tagged MARK3 expressed in baculovirus expression system using serine/threonine-25 peptide as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged PIM1 expressed in baculovirus expression system using serine/threonine-7 peptide as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged TIE2 (817 to 1101 residues) expressed in baculovirus expression system using tyrosine-5 peptide as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human GST-tagged MST3 expressed in baculovirus expression system using serine/threonine-7 peptide as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged ABL1 T315I mutant cytoplasmic domain expressed in baculovirus expression system using tyrosine...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human His-tagged ABL1 cytoplasmic domain expressed in baculovirus expression system using tyrosine-2 peptide as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length GST-tagged human PKN1 expressed in baculovirus expression system using Ser/Thr 07 as substrate in presence of A...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged ROCK1 catalytic domain expressed in baculovirus expression system using serine/threonine-7 peptide as subs...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PIK3C2alpha catalytic domain expressed in baculovirus expression system using PI li...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged TYK2 catalytic domain (833 to 1187 residues) expressed in baculovirus expression system using tyrosine-3 p...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged PDGFRalpha V561D mutant cytoplasmic domain expressed in baculovirus expression system using tyrosine-4 pep...More data for this Ligand-Target Pair