Compile Data Set for Download or QSAR

Found 11 hits of Enzyme Inhibition Constant Data   

Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22472(2-Amino-1,3-thiazol-4(5H)-one, 7b | 5,5-diethyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22459(2-(cyclooctylamino)-5-methyl-5-propyl-4,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22473(2-(hexahydro-2,5-methanopentalen-3a(1H)-ylamino)-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22458(2-(cyclooctylamino)-5-ethyl-5-methyl-4,5-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22457(2-(cycloheptylamino)-5-methyl-5-propyl-4,5-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22466(2-Amino-1,3-thiazol-4(5H)-one, 5h | 5-ethyl-5-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22470(2-(cyclooctylamino)-5,5-diethyl-4,5-dihydro-1,3-th...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22471(2-(cyclooctylamino)-1-thia-3-azaspiro[4.4]non-2-en...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22465(2-Amino-1,3-thiazol-4(5H)-one, 6g | 2-{bicyclo[2.2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22462(2-Amino-1,3-thiazol-4(5H)-one, 5f | 2-{bicyclo[2.2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum AB

LigandPNGBDBM22456(2-(cycloheptylamino)-5-ethyl-5-methyl-4,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM56Q8PubMed
* indicates data uncertainty>20%