Compile Data Set for Download or QSAR

Found 15 hits of Enzyme Inhibition Constant Data   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246298(CHEMBL487067 | N-(2-hydroxyethyl)-4-(4-(1-isopropy...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246301(4-(4-(1-cyclopentyl-2-methyl-1H-imidazol-5-yl)pyri...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246350(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246447(2-fluoro-4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246255(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246349(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246254(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246397(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246256(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246448(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246297(CHEMBL487066 | N-cyclopropyl-4-(4-(1-isopropyl-2-m...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246300(4-(4-(1-(cyclopropylmethyl)-2-methyl-1H-imidazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246299(4-(4-(1-ethyl-2-methyl-1H-imidazol-5-yl)pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246347(4-(4-(1-isopropyl-2-(methoxymethyl)-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246346(4-(4-(2-cyclopropyl-1-isopropyl-1H-imidazol-5-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
* indicates data uncertainty>20%