Compile Data Set for Download or QSAR

Found 14 hits of Enzyme Inhibition Constant Data   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297081((S)-N-(cyclobutylmethyl)-2-phenoxy-N-(pyrrolidin-3...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297087((S)-N-isobutyl-2-phenoxy-N-(pyrrolidin-3-yl)benzam...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297080((S)-N-(cyclobutylmethyl)-2-cyclopentyl-N-(pyrrolid...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297078((S)-N-(cyclobutylmethyl)-2-(ethylthio)-N-(pyrrolid...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50262678((S)-ethyl biphenyl-2-ylmethyl(pyrrolidin-3-yl)carb...)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297083((S)-N-phenyl-N-(pyrrolidin-3-yl)-2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297079((S)-N-(cyclobutylmethyl)-2-isopropyl-N-(pyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297086((S)-N-cyclobutyl-2-phenoxy-N-(pyrrolidin-3-yl)benz...)copy SMILEScopy InChI
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50236389(CHEMBL273208 | N-methyl(6-methyl-4-(2-phenoxypheno...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297088((S)-2-phenoxy-N-phenyl-N-(pyrrolidin-3-yl)benzamid...)copy SMILEScopy InChI
Affinity DataIC50: 5.54E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297077((S)-N-(cyclobutylmethyl)-N-(pyrrolidin-3-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297084((S)-N-cyclopentyl-2-isopropyl-N-(pyrrolidin-3-yl)b...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297082((S)-N-cyclobutyl-2-(methylthio)-N-(pyrrolidin-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297085((S)-N-ethyl-2-phenoxy-N-(pyrrolidin-3-yl)benzamide...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9J96PubMed
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