Compile Data Set for Download or QSAR

Found 20 hits of Enzyme Inhibition Constant Data   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274438(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28118(3-cyanoquinoline, 3 | 4-({3-chloro-4-[(1-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274439(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274204(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274440(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274335(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274333(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274385(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274384(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274334(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274332(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274386(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274245(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274437(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274202(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274203(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274244(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274243(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274242(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of MEK1 (unknown origin) by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274385(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)copy SMILEScopy InChI
Affinity DataIC50: 225nMAssay Description:Inhibition of MEK1-mediated ERK phosphorylation in human WM266-4 cells after 2.5 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FGDPubMed
* indicates data uncertainty>20%