Compile Data Set for Download or QSAR

Found 10 hits of Enzyme Inhibition Constant Data   

TargetGlutamate receptor 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)copy SMILEScopy InChI
Affinity DataKi:  1.74E+3nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)copy SMILEScopy InChI
Affinity DataKi:  2.26E+3nMAssay Description:Displacement of [3H]AMPA from GluA2 LBD (unknown origin) incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50304101((RS)-2-Amino-3-(5,6-dichloro-3'-hydroxybiphenyl-3-...)copy SMILEScopy InChI
Affinity DataKi:  5.03E+3nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ34JKPubMed
TargetGlutamate receptor 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)copy SMILEScopy InChI
Affinity DataKi:  2.40E+4nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)copy SMILEScopy InChI
Affinity DataKi:  8.40E+4nMAssay Description:Displacement of [3H]AMPA from GluA2 LBD (unknown origin) incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142615(CHEMBL3759684)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ34JKPubMed
TargetGlutamate receptor 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142617(CHEMBL3758644)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ34JKPubMed
TargetGlutamate receptor 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142614(CHEMBL3758336)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Antagonist activity against recombinant rat GluA2(Q)i expressed in xenopus oocytes assessed as inhibition of L-glutamate-induced intracellular calciu...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Antagonist activity against recombinant rat GluA2(Q)i expressed in xenopus oocytes assessed as inhibition of L-glutamate-induced intracellular calciu...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50192229(3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-1,1-dioxo-...)copy SMILEScopy InChI
Affinity DataEC50:  7.60E+3nMAssay Description:Agonist activity at human GluA2(Q)i expressed in HEK293 cells assessed as enhancement of glutamate-evoked desensitized current by whole cell patch cl...More data for this Ligand-Target Pair
* indicates data uncertainty>20%