Found 32 hits of Enzyme Inhibition Constant Data
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 0.0680nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Agonist activity at MT1 receptor (unknown origin) expressed in mouse NIH3T3 cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to MT1 receptor (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity to MT1 receptor (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 0.630nMAssay Description:Displacement of [125I]2-iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to MT1 receptor (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Agonist activity at MT1 receptor (unknown origin) expressed in mouse NIH3T3 cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]2-iodomelatonin from MT1 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Agonist activity at MT1 receptor (unknown origin) expressed in HEK293 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Displacement of [125I]2-iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Displacement of [125I]2-iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Displacement of [125I]2-iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Displacement of [125I]2-iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Displacement of [125I]2-iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 7.90nMAssay Description:Displacement of [125I]2-iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of [125I]2-iodomelatonin from MT1 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Antagonist activity at MT1 receptor (unknown origin) expressed in mouse NIH3T3 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Displacement of [125I]2-iodomelatonin from MT1 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 158nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 207nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 501nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 1.29E+3nMAssay Description:Antagonist activity at human MT1 receptorMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Binding affinity to MT1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Binding affinity to MT1 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at MT1 receptor (unknown origin) assessed as cAMP accumulationMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
The German University in Cairo
Curated by ChEMBL
The German University in Cairo
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at MT1 receptor (unknown origin) assessed as cAMP accumulationMore data for this Ligand-Target Pair