Found 82 hits of Enzyme Inhibition Constant Data
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of full-length human C-terminal NanoLuc-tagged P38 alpha MAPK expressed in human HEK293T cells incubated for 2 hrs followed by NanoBRET Na...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 258nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University
Curated by ChEMBL
Johann Wolfgang Goethe-University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
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