Found 41 hits of Enzyme Inhibition Constant Data
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC
Curated by ChEMBL
OSI Pharmaceuticals LLC
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair