Compile Data Set for Download or QSAR

Found 15 hits of Enzyme Inhibition Constant Data   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419191(CHEMBL1828845)copy SMILEScopy InChI
Affinity DataKi:  3.98E+3nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)copy SMILEScopy InChI
Affinity DataKi:  7.94E+3nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419180(CHEMBL1831037)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419188(CHEMBL1616460)copy SMILEScopy InChI
Affinity DataKi:  1.58E+4nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM74511(1-(1-benzothien-3-ylmethyl)piperidine | 1-(1-benzo...)copy SMILEScopy InChI
Affinity DataKi:  1.58E+4nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419185(CHEMBL1831048)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419187(CHEMBL1624521)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50419176(CHEMBL1831027)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in human SH-SY5Y cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50353946(CHEMBL1831032)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus oocytes assessed as increase of acetylcholine-induced effect by electrophysiology assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50353945(CHEMBL1831033)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus oocytes assessed as increase of acetylcholine-induced effect by electrophysiology assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50353948(CHEMBL1831043)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus oocytes assessed as increase of acetylcholine-induced effect by electrophysiology assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50353947(CHEMBL1831030)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus oocytes assessed as increase of acetylcholine-induced effect by electrophysiology assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50353949(CHEMBL1831038)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus oocytes assessed as increase of acetylcholine-induced effect by electrophysiology assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
VU University Amsterdam

Curated by ChEMBL
LigandPNGBDBM50353944(CHEMBL1831036)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus oocytes assessed as increase of acetylcholine-induced effect by electrophysiology assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09BHPubMed
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