Compile Data Set for Download or QSAR

Found 14 hits of Enzyme Inhibition Constant Data   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM50029600(5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 68nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM50029600(5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 71nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113768((E)-N-(3,4-Dihydroxyphenethyl)-6-((1R,2R)-3,3-dime...)copy SMILEScopy InChI
Affinity DataIC50: 800nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113767((E)-6-((1R,2R)-3,3-Dimethyl-2-(3-methylbut-3-enyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113768((E)-N-(3,4-Dihydroxyphenethyl)-6-((1R,2R)-3,3-dime...)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+3nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113767((E)-6-((1R,2R)-3,3-Dimethyl-2-(3-methylbut-3-enyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113765((E)-N-Allyl-6-((1R,2R)-3,3-dimethyl-2-(3-methylbut...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113765((E)-N-Allyl-6-((1R,2R)-3,3-dimethyl-2-(3-methylbut...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113763(β-Caryophyllene (1) | β-humulene | (W...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113764((E)-6-((1R,2R)-3,3-Dimethyl-2-(3-methylbut-3-enyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113766((E)-N-(2-Chloroethyl)-6-((1R,2R)-3,3-dimethyl-2-(3...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113763(β-Caryophyllene (1) | β-humulene | (W...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113766((E)-N-(2-Chloroethyl)-6-((1R,2R)-3,3-dimethyl-2-(3...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Bern , Bühlstrasse 28, CH-3012 Bern, Switzerland.

LigandPNGBDBM113764((E)-6-((1R,2R)-3,3-Dimethyl-2-(3-methylbut-3-enyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T15295PubMed
* indicates data uncertainty>20%