Compile Data Set for Download or QSAR

Found 25 hits of Enzyme Inhibition Constant Data   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333973(CHEMBL1644606 | exo-3'-((1R,5S)-8-azabicyclo[3.2.1...)copy SMILEScopy InChI
Affinity DataIC50: 173nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333959(CHEMBL1644476 | exo-(1R,5S)-3-(3-bromophenoxy)-8-a...)copy SMILEScopy InChI
Affinity DataIC50: 201nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333957(CHEMBL1644474 | exo-(1R,5S)-3-(3-chlorophenoxy)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333955(CHEMBL1644472 | exo-(1R,5S)-8-methyl-3-phenoxy-8-a...)copy SMILEScopy InChI
Affinity DataIC50: 437nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333974(CHEMBL1644607 | exo-3'-((1R,5S)-8-azabicyclo[3.2.1...)copy SMILEScopy InChI
Affinity DataIC50: 481nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333978(CHEMBL1644471 | exo-(1R,5S)-3-phenoxy-8-azabicyclo...)copy SMILEScopy InChI
Affinity DataIC50: 737nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333961(CHEMBL1644478 | exo-(1R,5S)-3-(3-fluorophenoxy)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333960(CHEMBL1644477 | exo-(1R,5S)-3-(3-iodophenoxy)-8-az...)copy SMILEScopy InChI
Affinity DataIC50: 804nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333958(CHEMBL1644475 | exo-(1R,5S)-3-(2-chlorophenoxy)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333966(CHEMBL1644483 | exo-3-((1R,5S)-8-azabicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333963(CHEMBL1644480 | exo-(1R,5S)-3-(3-nitrophenoxy)-8-a...)copy SMILEScopy InChI
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333956(CHEMBL1644473 | exo-(1R,5S)-3-(4-chlorophenoxy)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333962(CHEMBL1644479 | exo-(1R,5S)-3-(m-tolyloxy)-8-azabi...)copy SMILEScopy InChI
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333965(CHEMBL1644482 | exo-(1R,5S)-3-(3-methoxyphenoxy)-8...)copy SMILEScopy InChI
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333964(CHEMBL1644481 | exo-(1R,5S)-3-(3-(trifluoromethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333969(CHEMBL1644602 | exo-(1R,5S)-3-(5-chlorobiphenyl-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5.33E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333975(CHEMBL1644608 | exo-3'-((1R,5S)-8-azabicyclo[3.2.1...)copy SMILEScopy InChI
Affinity DataIC50: 8.07E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333970(CHEMBL1644603 | exo-(1R,5S)-3-(5-fluorobiphenyl-3-...)copy SMILEScopy InChI
Affinity DataIC50: 8.71E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333971(CHEMBL1644604 | exo-5-((1R,5S)-8-azabicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 9.55E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333968(CHEMBL1644601 | exo-(1R,5S)-3-(5-bromobiphenyl-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333952(CHEMBL1644470 | exo-(1R,5S)-3-(6-phenylpyridin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333976(CHEMBL1644609 | exo-2-(6-((1R,5S)-8-azabicyclo[3.2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333967(CHEMBL1644600 | exo-(1R,5S)-3-(5-(trifluoromethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333972(CHEMBL1644605 | exo-2-((1R,5S)-8-azabicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50333977(CHEMBL1644610 | exo-2-((1R,5S)-8-azabicyclo[3.2.1]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ37D3PubMed
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