Compile Data Set for Download or QSAR

Found 25 hits of Enzyme Inhibition Constant Data   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183546(CHEMBL383071 | S-(+)-4-[2-[bis-(4-fluorophenyl)met...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Inhibition of [3H]NE uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183532(4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1-(3,4-di...)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183538((R)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)copy SMILEScopy InChI
Affinity DataKi:  79nMAssay Description:Inhibition of [3H]NE uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183545(CHEMBL444540 | R-(-)-4-[2-[bis-(4-fluorophenyl)met...)copy SMILEScopy InChI
Affinity DataKi:  103nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183543((R)-(-)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)copy SMILEScopy InChI
Affinity DataKi:  143nMAssay Description:Inhibition of [3H]NE uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183544(CHEMBL202644 | S-(+)-4-[2-[bis-(4-fluorophenyl)met...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Inhibition of [3H]NE uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183533((S)-(-)-4-(2-benzhydryloxyethyl)-1-(3-phenylpropan...)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183535((R)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)copy SMILEScopy InChI
Affinity DataKi:  330nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183537((S)-(+)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)copy SMILEScopy InChI
Affinity DataKi:  338nMAssay Description:Inhibition of [3H]NE uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183546(CHEMBL383071 | S-(+)-4-[2-[bis-(4-fluorophenyl)met...)copy SMILEScopy InChI
Affinity DataKi:  340nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183547(CHEMBL206128 | CHEMBL255065 | trans-(S,S)-4-[2-[bi...)copy SMILEScopy InChI
Affinity DataKi:  359nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183549((S)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)copy SMILEScopy InChI
Affinity DataKi:  361nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183544(CHEMBL202644 | S-(+)-4-[2-[bis-(4-fluorophenyl)met...)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183534((R)-(-)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)copy SMILEScopy InChI
Affinity DataKi:  402nMAssay Description:Inhibition of [3H]NE uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183540((S)-(-)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)copy SMILEScopy InChI
Affinity DataKi:  440nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183538((R)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)copy SMILEScopy InChI
Affinity DataKi:  460nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183548((S)-(+)-4-(2-benzhydryloxyethyl)-1-(3-phenylpropan...)copy SMILEScopy InChI
Affinity DataKi:  485nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183541(CHEMBL424682 | R-(-)-4-[2-[bis-(4-fluorophenyl)met...)copy SMILEScopy InChI
Affinity DataKi:  560nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183542((S)-(-)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)copy SMILEScopy InChI
Affinity DataKi:  736nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183536((R)-(-)-4-(2-benzhydryloxyethyl)-1-(3-phenylpropan...)copy SMILEScopy InChI
Affinity DataKi:  785nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183537((S)-(+)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)copy SMILEScopy InChI
Affinity DataKi:  851nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183534((R)-(-)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)copy SMILEScopy InChI
Affinity DataKi:  941nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183539(CHEMBL381256 | CHEMBL429492 | trans-(R,R)-4-[2-[bi...)copy SMILEScopy InChI
Affinity DataKi:  947nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183543((R)-(-)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)copy SMILEScopy InChI
Affinity DataKi:  1.22E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NIDDK

Curated by ChEMBL
LigandPNGBDBM50183550((R)-(+)-4-(2-benzhydryloxyethyl)-1-(3-phenylpropan...)copy SMILEScopy InChI
Affinity DataKi: >5.60E+3nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KS6R5FPubMed
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