Compile Data Set for Download or QSAR

Found 13 hits of Enzyme Inhibition Constant Data   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049946(CHEMBL3317694)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049950(CHEMBL3317704)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049936(CHEMBL3317703)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049937(CHEMBL3317702)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049948(CHEMBL3317705)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049939(CHEMBL3317700)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049938(CHEMBL3317701)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049944(CHEMBL3317696)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049943(CHEMBL3317697)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049947(CHEMBL3353960)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049945(CHEMBL3317695)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049942(CHEMBL3317698)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50049940(CHEMBL3317699)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in CHO cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87CF9PubMed
* indicates data uncertainty>20%