Affinity Data by PubMed id=16366598

Found 1 hit of Enzyme Inhibition Constant Data

Tyrosine-protein kinase Fyn(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL

BDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI

IC50: 378nMAssay Description:Inhibitory activity against FYNMore data for this Ligand-Target Pair

Displayed 1 to 50 (of 51 total ) | Next | Last >>* indicates data uncertainty>20%

Targets 20 ▿
- Platelet-derived growth factor receptor beta 32
- Mitogen-activated protein kinase 1 1
- Tyrosine-protein kinase Lck 1
- Glycogen synthase kinase-3 1
- Tyrosine-protein kinase ABL1 1
- Tyrosine-protein kinase Fyn 1
- Cyclin-dependent kinase 7 1
- Focal adhesion kinase 1 1
- Receptor tyrosine-protein kinase erbB-2 1
- Cyclin-dependent kinase 4 1
- Epidermal growth factor receptor 1
- Platelet-derived growth factor receptor alpha 1
- Casein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2 1
- Cyclin-dependent kinase 2 1
- Cyclin-dependent kinase 1 1
- cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma 1
- Proto-oncogene tyrosine-protein kinase Src 1
- Vascular endothelial growth factor receptor 1/2/3 1
- Insulin receptor 1
- Fibroblast growth factor receptor 1 1
Publications 1 ▿
- J Med Chem 48: 8163-73 (2005) 51
Institutions 1 ▿
- [Johnson & Johnson Pharmaceutical Research and Development] 51
Affinity: 1 to 1.0E+5 nM▿
- IC50 51
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 1