Compile Data Set for Download or QSAR

Found 19 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50275935((S)-2-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  240nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50275934((2-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)thia...)copy SMILEScopy InChI
Affinity DataKi:  270nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50276018(1-(3-(cyclopenta-1,3-dienyl)benzyl)-3,5-diethylben...)copy SMILEScopy InChI
Affinity DataKi:  318nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50276064(CHEMBL470780 | N-(3,5-dimethylphenyl)-4-(5-methylt...)copy SMILEScopy InChI
Affinity DataKi:  410nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50276015(CHEMBL509161 | N-(3,5-dimethylphenyl)-4-(thiazol-2...)copy SMILEScopy InChI
Affinity DataKi:  419nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50276065((2-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)thia...)copy SMILEScopy InChI
Affinity DataKi:  450nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50249318(2-(2-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-4...)copy SMILEScopy InChI
Affinity DataKi:  560nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50249286(3-(3-(4-(thiazol-2-yl)pyrimidin-2-ylamino)-5-(trif...)copy SMILEScopy InChI
Affinity DataKi:  677nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50275356(3-(4-(4-(hydroxymethyl)thiazol-2-yl)pyrimidin-2-yl...)copy SMILEScopy InChI
Affinity DataKi:  680nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50275358((2-(2-(3-methyl-5-(trifluoromethyl)phenylamino)pyr...)copy SMILEScopy InChI
Affinity DataKi:  750nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50276017(3-(4-(thiazol-2-yl)pyrimidin-2-ylamino)-5-(trifluo...)copy SMILEScopy InChI
Affinity DataKi:  754nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50249416(CHEMBL471776 | N-(3-methyl-5-(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataKi:  891nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50275355((2-(2-(3-methoxy-5-(trifluoromethyl)phenylamino)py...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50249356(CHEMBL453217 | N-(3,5-dimethylphenyl)-4-(4-methylt...)copy SMILEScopy InChI
Affinity DataKi:  1.03E+3nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50275357(CHEMBL451450 | N-(3-methoxy-5-(trifluoromethyl)phe...)copy SMILEScopy InChI
Affinity DataKi:  1.14E+3nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50249540((R)-2-(2-(3,5-dimethylphenylamino)pyrimidin-4-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50276063(4-(thiazol-2-yl)-N-m-tolylpyrimidin-2-amine | CHEM...)copy SMILEScopy InChI
Affinity DataKi:  1.55E+3nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50276016(CHEMBL512319 | N-(3-methoxy-5-(trifluoromethyl)phe...)copy SMILEScopy InChI
Affinity DataKi:  2.15E+3nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50249284(2-(4-methyl-2-(2-(3-methyl-5-(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
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