Compile Data Set for Download or QSAR

Found 11 hits of Enzyme Inhibition Constant Data   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141580(4-(3-Chloro-4-methoxy-benzylamino)-8-ethyl-3-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141584(4-(3-Chloro-4-methoxy-benzylamino)-8-ethyl-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141588(4-(3-Chloro-4-methoxy-benzylamino)-3-hydroxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141586(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-8-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141583(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-8-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141587(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141582(4-(3-Chloro-4-methoxy-benzylamino)-quinoline-6-car...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141579(4-(3-Chloro-4-methoxy-benzylamino)-6-cyano-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141585(4-(3-Chloro-4-methoxy-benzylamino)-6-trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50141581(4-(3-Chloro-4-methoxy-benzylamino)-7-trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G1607QPubMed
* indicates data uncertainty>20%