Compile Data Set for Download or QSAR

Found 44 hits of Enzyme Inhibition Constant Data   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326233(CHEMBL1243011 | N-{1-[3-(5-Fluoro-2-oxo-3,4-dihydr...)copy SMILEScopy InChI
Affinity DataEC50:  150nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50003359(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...)copy SMILEScopy InChI
Affinity DataEC50:  6.20nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in BHK-21 cells coexpressing Galpha16 subunit assessed as increase of acetylcholine-induce...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326240(CHEMBL1243138 | N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326227(CHEMBL1243386 | N-{1-[3-(8-Fluoro-2-oxo-3,4-dihydr...)copy SMILEScopy InChI
Affinity DataEC50:  310nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)copy SMILEScopy InChI
Affinity DataEC50:  220nMAssay Description:Agonist activity at human muscarinic M2 receptor expressed in CHO-K1 cells coexpressing Galpha16 subunit assessed as increase of acetylcholine-induce...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in BHK-21 cells coexpressing Galpha16 subunit assessed as increase of acetylcholine-induce...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326217(CHEMBL1242979 | N-{1-[3-(6,7-Difluoro-2-oxo-3,4-di...)copy SMILEScopy InChI
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326237(CHEMBL1243075 | N-{1-[3-(6-Methoxy-2-oxo-3,4-dihyd...)copy SMILEScopy InChI
Affinity DataEC50:  560nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326241(CHEMBL1243139 | N-(1-(3-(2-oxobenzo[d]oxazol-3(2H)...)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326244(CHEMBL1243202 | N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1...)copy SMILEScopy InChI
Affinity DataEC50:  180nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326221(CHEMBL1243267 | Cyclopropanecarboxylic acid{1-[3-(...)copy SMILEScopy InChI
Affinity DataEC50:  110nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326223(CHEMBL1243296 | Cyclopentanecarboxylic acid{1-[3-(...)copy SMILEScopy InChI
Affinity DataEC50:  350nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)copy SMILEScopy InChI
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326231(CHEMBL1242951 | N-{1-[3-(6,7-Difluoro-2-oxo-3,4-di...)copy SMILEScopy InChI
Affinity DataEC50:  15nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50003359(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...)copy SMILEScopy InChI
Affinity DataEC50:  140nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)copy SMILEScopy InChI
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326245(CHEMBL1243232 | N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1...)copy SMILEScopy InChI
Affinity DataEC50:  27nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326225(CHEMBL1243357 | N-{1-[3-(6-Fluoro-2-oxo-3,4-dihydr...)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326230(CHEMBL1242925 | N-{1-[3-(6,7-Difluoro-3-oxo-2,3-di...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326234(CHEMBL1243043 | N-{1-[3-(6-Fluoro-2-oxo-3,4-dihydr...)copy SMILEScopy InChI
Affinity DataEC50:  49nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326242(CHEMBL1243168 | N-Methyl-N-{1-[3-(3-oxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataEC50:  910nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326226(CHEMBL1243358 | N-{1-[3-(7-Fluoro-2-oxo-3,4-dihydr...)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326228(CHEMBL1243387 | N-{1-[3-(6,7-Difluoro-2-oxo-3,4-di...)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50003359(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...)copy SMILEScopy InChI
Affinity DataEC50:  120nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326218(CHEMBL1242923 | N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,...)copy SMILEScopy InChI
Affinity DataEC50:  61nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50003359(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...)copy SMILEScopy InChI
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50263887(1-(1'-(2-methylbenzyl)-1,4'-bipiperidin-4-yl)-1H-b...)copy SMILEScopy InChI
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326235(CHEMBL1243044 | N-{1-[3-(7-Fluoro-2-oxo-3,4-dihydr...)copy SMILEScopy InChI
Affinity DataEC50:  51nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326236(CHEMBL1243074 | N-{1-[3-(8-Fluoro-2-oxo-3,4-dihydr...)copy SMILEScopy InChI
Affinity DataEC50:  290nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326239(CHEMBL1243110 | N-{1-[3-(2-Oxo-3,4-dihydro-2H-quin...)copy SMILEScopy InChI
Affinity DataEC50:  48nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326243(CHEMBL1243201 | N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1...)copy SMILEScopy InChI
Affinity DataEC50:  970nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326224(CHEMBL1243328 | N-{1-[3-(5-Fluoro-2-oxo-3,4-dihydr...)copy SMILEScopy InChI
Affinity DataEC50:  19nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326229(CHEMBL1242924 | N-{1-[3-(6,7-Difluoro-2-oxo-3,4-di...)copy SMILEScopy InChI
Affinity DataEC50:  86nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM10759(2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...)copy SMILEScopy InChI
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50122054(8-Chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]dia...)copy SMILEScopy InChI
Affinity DataEC50:  170nMAssay Description:Agonist activity at human muscarinic M5 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326219(4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one | C...)copy SMILEScopy InChI
Affinity DataEC50:  150nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50122054(8-Chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]dia...)copy SMILEScopy InChI
Affinity DataEC50:  18nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326217(CHEMBL1242979 | N-{1-[3-(6,7-Difluoro-2-oxo-3,4-di...)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326220(CHEMBL1243233 | N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1...)copy SMILEScopy InChI
Affinity DataEC50:  46nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326222(CHEMBL1243295 | Cyclobutanecarboxylic acid{1-[3-(3...)copy SMILEScopy InChI
Affinity DataEC50:  160nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50122054(8-Chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]dia...)copy SMILEScopy InChI
Affinity DataEC50:  400nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in BHK-21 cells coexpressing Galpha16 subunit assessed as increase of acetylcholine-induce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326217(CHEMBL1242979 | N-{1-[3-(6,7-Difluoro-2-oxo-3,4-di...)copy SMILEScopy InChI
Affinity DataEC50:  300nMAssay Description:Agonist activity at human muscarinic M4 receptor expressed in BHK-21 cells coexpressing Galpha16 subunit assessed as increase of acetylcholine-induce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326232(2-(3-Methoxy-phenyl)-N-{1-[3-(3-oxo-2,3-dihydro-be...)copy SMILEScopy InChI
Affinity DataEC50:  130nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50326238(CHEMBL1243109 | N-{1-[3-(7-Methoxy-2-oxo-3,4-dihyd...)copy SMILEScopy InChI
Affinity DataEC50:  120nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765G9KPubMed
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