Found 20 hits of Enzyme Inhibition Constant Data
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 5.60E+3nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 520nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 180nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 170nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 190nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 52nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 290nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 280nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 640nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 310nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 310nMAssay Description:Inhibition of PERK-mediated protein synthesis in human U2OS cells harboring thapsigargin-induced ER stress assessed as incorporation of L-azidohomoal...More data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Inhibition of B-Raf in human MIAPaCa2 cells assessed as inhibition of MAPK signaling by immunoblot analysisMore data for this Ligand-Target Pair