Compile Data Set for Download or QSAR

Found 20 hits of Enzyme Inhibition Constant Data   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254113((R)-4-(3,4-dichlorophenyl)-4-(1H-indol-4-yl)-N-met...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254027((R)-3-(3,4-dichlorophenyl)-3-(1H-indol-4-yl)-N-met...)copy SMILEScopy InChI
Affinity DataIC50: 7.21nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254075((R)-3-(3,4-dichlorophenyl)-N-methyl-3-(naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254112((S)-4-(1-(3,4-dimethylphenyl)hexyl)-1H-indene hydr...)copy SMILEScopy InChI
Affinity DataIC50: 14.3nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254111((S)-3-(3,4-dichlorophenyl)-3-(1H-indol-4-yl)-N-met...)copy SMILEScopy InChI
Affinity DataIC50: 14.9nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254074((S)-3-(3,4-dichlorophenyl)-N-methyl-3-(naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 35.8nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254110((R)-4-(3,4-dichlorophenyl)-N-methyl-4-(naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 61.2nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254076((S)-4-(3,4-dichlorophenyl)-N-methyl-4-(naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 209nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254046((R)-N-methyl-3-(naphthalen-1-yl)-3-(thiophen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254071((S)-3-(1H-indol-4-yl)-N-methyl-3-(thiophen-2-yl)pr...)copy SMILEScopy InChI
Affinity DataIC50: 292nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254047((S)-N-methyl-3-(naphthalen-1-yl)-3-(thiophen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 309nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254073((S)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...)copy SMILEScopy InChI
Affinity DataIC50: 318nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254048((R)-N-methyl-4-(naphthalen-1-yl)-4-(thiophen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 405nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254049((S)-N-methyl-4-(naphthalen-1-yl)-4-(thiophen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 466nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254050((R)-3-(1H-indol-4-yl)-N-methyl-3-(thiophen-2-yl)pr...)copy SMILEScopy InChI
Affinity DataIC50: 572nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50136674((3R)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propa...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254072((R)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...)copy SMILEScopy InChI
Affinity DataIC50: 957nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50366567(ATOMOXETINE)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The State University of New York

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58N95PubMed
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