Compile Data Set for Download or QSAR

Found 14 hits of Enzyme Inhibition Constant Data   

TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337198((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-carbamoyl-[...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337209(4-((S)-3-(((S)-1-((6-(Benzylcarbamoyl)-4'-cyano-[1...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337205(CHEMBL1684879 | Methyl 2'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337204(4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-cyano-[1...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337207(4-((S)-3-(((S)-1-((6-(Benzylcarbamoyl)-3'-carbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337206(4-((S)-3-(((S)-1-((6-(Benzylcarbamoyl)-3'-cyano-[1...)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337200(CHEMBL1681829 | Methyl 3'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337199(4-((S)-3-((S)-1-(6-(Benzylcarbamoyl)-4'-carbamoylb...)copy SMILEScopy InChI
Affinity DataIC50: 7.31E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337201(4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-3'-cyano-[1...)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337196(CHEMBL1684875 | N2-benzyl-5-((S)-2-((S)-2-(4-cyano...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337203(CHEMBL1681826 | Methyl 3'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337202(4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-3'-carbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337197(CHEMBL1684876 | N3-benzyl-5-((S)-2-((S)-2-(4-cyano...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337208(CHEMBL1684874 | Methyl 2'-(benzylcarbamoyl)-5'-((S...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ4058PubMed
* indicates data uncertainty>20%