Compile Data Set for Download or QSAR

Found 34 hits of Enzyme Inhibition Constant Data   

TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50017712((-)-reserpine | (3beta,16beta,17alpha,18beta,20alp...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459625(CHEMBL4205254)copy SMILEScopy InChI
Affinity DataIC50: 3.39nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459625(CHEMBL4205254)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459621(CHEMBL4202787)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459630(CHEMBL4207658)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459627(CHEMBL4208779)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50017712((-)-reserpine | (3beta,16beta,17alpha,18beta,20alp...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459625(CHEMBL4205254)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459625(CHEMBL4205254)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459619(CHEMBL4206824)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459630(CHEMBL4207658)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459626(CHEMBL4214975)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459619(CHEMBL4206824)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459628(CHEMBL4208250)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459621(CHEMBL4202787)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50192902(2-ethyl-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-he...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459626(CHEMBL4214975)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459628(CHEMBL4208250)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459627(CHEMBL4208779)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459617(CHEMBL4213176)copy SMILEScopy InChI
Affinity DataIC50: 142nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50192902(2-ethyl-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-he...)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50080818((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 381nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459618(CHEMBL4216117)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Mus musculus)
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)copy SMILEScopy InChI
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of VMAT2 in C57Bl/6J mouse striatal membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addition ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459624(CHEMBL4203894)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50009057((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)copy SMILEScopy InChI
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50080818((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459620(CHEMBL4204449)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459622(CHEMBL4217581)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
TargetSynaptic vesicular amine transporter(Homo sapiens (Human))
Organix Inc

Curated by ChEMBL
LigandPNGBDBM50459623(CHEMBL4212633)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human VMAT2 expressed in HEK293 cell membranes assessed as reduction in [3H[-5HT uptake pre-incubated for 10 mins before [3H[-5HT addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QZ9PubMed
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