Found 19 hits of Enzyme Inhibition Constant Data
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.39E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.64E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.78E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.55E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 4.73E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 8.19E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Cambridge NeuroScience, Inc.
Curated by ChEMBL
Affinity DataIC50: 9.21E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair