Compile Data Set for Download or QSAR

Found 16 hits of Enzyme Inhibition Constant Data   

TargetLeukocyte tyrosine kinase receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396263(CHEMBL2172315)copy SMILEScopy InChI
Affinity DataKd:  8.20nMAssay Description:Binding affinity to human LTK by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396263(CHEMBL2172315)copy SMILEScopy InChI
Affinity DataKd:  72nMAssay Description:Binding affinity to human MER by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396243(CHEMBL2172308 | US10370379, Compound TSR-011)copy SMILEScopy InChI
Affinity DataKd:  28nMAssay Description:Binding affinity to human LCK by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetLeukocyte tyrosine kinase receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396243(CHEMBL2172308 | US10370379, Compound TSR-011)copy SMILEScopy InChI
Affinity DataKd:  2.5nMAssay Description:Binding affinity to human LTK by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396263(CHEMBL2172315)copy SMILEScopy InChI
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to human AXL by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396263(CHEMBL2172315)copy SMILEScopy InChI
Affinity DataKd:  5.60nMAssay Description:Binding affinity to human IRAK1 by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetMitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396243(CHEMBL2172308 | US10370379, Compound TSR-011)copy SMILEScopy InChI
Affinity DataKd:  11nMAssay Description:Binding affinity to human MAP4K2 by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetMitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396263(CHEMBL2172315)copy SMILEScopy InChI
Affinity DataKd:  25nMAssay Description:Binding affinity to human MAP4K2 by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396243(CHEMBL2172308 | US10370379, Compound TSR-011)copy SMILEScopy InChI
Affinity DataKd:  0.360nMAssay Description:Binding affinity to human ALK by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396263(CHEMBL2172315)copy SMILEScopy InChI
Affinity DataKd:  0.240nMAssay Description:Binding affinity to human ALK by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396243(CHEMBL2172308 | US10370379, Compound TSR-011)copy SMILEScopy InChI
Affinity DataKd:  18nMAssay Description:Binding affinity to human MER by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396243(CHEMBL2172308 | US10370379, Compound TSR-011)copy SMILEScopy InChI
Affinity DataKd:  42nMAssay Description:Binding affinity to human FLT3 by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetInsulin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396263(CHEMBL2172315)copy SMILEScopy InChI
Affinity DataKd:  72nMAssay Description:Binding affinity to human INSR by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396263(CHEMBL2172315)copy SMILEScopy InChI
Affinity DataKd:  110nMAssay Description:Binding affinity to human LCK by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396243(CHEMBL2172308 | US10370379, Compound TSR-011)copy SMILEScopy InChI
Affinity DataKd:  5.70nMAssay Description:Binding affinity to human IRAK1 by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50396243(CHEMBL2172308 | US10370379, Compound TSR-011)copy SMILEScopy InChI
Affinity DataKd:  29nMAssay Description:Binding affinity to human AXL by Ambit titration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M046KTPubMed
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