Compile Data Set for Download or QSAR

Found 10 hits of Enzyme Inhibition Constant Data   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50319660((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  12.2nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HVQPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50319665((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  12.8nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HVQPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50319664((R,S)-2-((+/-)-exo-Bicyclo[2.2.1]heptan-2-ylamino)...)copy SMILEScopy InChI
Affinity DataKi:  17.3nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HVQPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50319666((S)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  27.8nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HVQPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50319667((R)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  30.6nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HVQPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50319668((R)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  47.2nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HVQPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50319659(2-(bicyclo[2.2.1]heptan-2-ylamino)-5-isopropylthia...)copy SMILEScopy InChI
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HVQPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50319661((R)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  227nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HVQPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50319660((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  329nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HVQPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50319661((R)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  770nMAssay Description:Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7HVQPubMed
* indicates data uncertainty>20%