Compile Data Set for Download or QSAR

Found 23 hits of Enzyme Inhibition Constant Data   

TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)copy SMILEScopy InChI
Affinity DataIC50: 15nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)copy SMILEScopy InChI
Affinity DataIC50: 25nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM50257541((1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 36nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM50257541((1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM87245(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 125nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123757(1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (...)copy SMILEScopy InChI
Affinity DataIC50: 150nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM87245(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 225nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM87245(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 255nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 350nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 385nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 426nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM87231(N-[2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-...)copy SMILEScopy InChI
Affinity DataIC50: 450nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123760(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (19))copy SMILEScopy InChI
Affinity DataIC50: 500nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D1(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM87231(N-[2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM50257541((1R,2R)-N-([S]-1-{4-[5-bromo-2-oxo-2,3-dihydro-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123757(1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM87231(N-[2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123760(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (19))copy SMILEScopy InChI
Affinity DataIC50: 1.25E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D2(Homo sapiens (Human))
University of Massachusetts Boston

LigandPNGBDBM123757(1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123760(3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (19))copy SMILEScopy InChI
Affinity DataIC50: 1.55E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123759(3‐(naphthalen‐2‐yl)‐1HR...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123758(3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (17))copy SMILEScopy InChI
Affinity DataIC50: 1.95E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2N05PubMed
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