Compile Data Set for Download or QSAR

Found 24 hits of Enzyme Inhibition Constant Data   

TargetGlutamate receptor ionotropic, kainate 1(RAT)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataKi:  2.13nMAssay Description:Displacement of [3H]SYM from rat recombinant GluR5(Q) RNA-edited isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataKi:  1.66E+3nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR2(R) RNA-edited flop isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMedMMDB
TargetGlutamate receptor 3(RAT)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataKi:  2.04E+3nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR3 flop isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor 4(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataKi:  2.14E+3nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR4 flop isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMedMMDB
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataKi:  2.53E+3nMAssay Description:Displacement of [3H]SYM from rat recombinant GluR7A expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataKi:  2.78E+3nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR1 flop isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]KA from rat recombinant GluR6(VCR) RNA-edited isoform expressed in baculovirus infected Sf9 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataEC50:  7.30E+5nMAssay Description:Agonist activity at rat recombinant GluR1 flip isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM ass...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor 3(RAT)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataEC50:  6.30E+5nMAssay Description:Agonist activity at rat recombinant GluR3 flip isomer expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assa...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor 4(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at rat recombinant GluR4 flip isomer expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assa...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)copy SMILEScopy InChI
Affinity DataEC50:  1.40E+5nMAssay Description:Agonist activity at rat recombinant GluR5(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat recombinant GluR2(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMedMMDB
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at rat recombinant GluR6(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo...Checked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at rat recombinant GluR3 flip isomer expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assa...Checked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataEC50:  3.80E+5nMAssay Description:Agonist activity at rat recombinant GluR2(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo...Checked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataEC50:  660nMAssay Description:Agonist activity at ConA-treated rat GluR5(Q) RNA-edited isoform expressed in Xenopus laevis oocytes assessed as glutamic acid-induced maximal curren...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)copy SMILEScopy InChI
Affinity DataEC50:  1.90E+5nMAssay Description:Agonist activity at rat recombinant GluR2(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor ionotropic, kainate 1(RAT)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataEC50:  3.70E+4nMAssay Description:Agonist activity at rat recombinant GluR5(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo...Checked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)copy SMILEScopy InChI
Affinity DataEC50:  5.10E+4nMAssay Description:Agonist activity at rat recombinant GluR1 flip isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM ass...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)copy SMILEScopy InChI
Affinity DataEC50:  7.30E+4nMAssay Description:Agonist activity at rat recombinant GluR6(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor 4(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataEC50:  4.70E+4nMAssay Description:Agonist activity at rat recombinant GluR4 flip isomer expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assa...Checked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataEC50:  2.30E+4nMAssay Description:Agonist activity at rat recombinant GluR1 flip isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM ass...Checked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)copy SMILEScopy InChI
Affinity DataEC50:  6.20E+4nMAssay Description:Agonist activity at ConA-treated rat GluR1 flip isoform expressed in Xenopus laevis oocytes assessed as glutamic acid-induced maximal current by two-...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
TargetGlutamate receptor 3(RAT)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)copy SMILEScopy InChI
Affinity DataEC50:  5.20E+4nMAssay Description:Agonist activity at rat recombinant GluR3 flip isomer expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assa...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49RP9PubMed
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