Compile Data Set for Download or QSAR

Found 11 hits of Enzyme Inhibition Constant Data   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000040(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance PMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75FCCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21016(CHEMBL22870 | L 732138 | L-732,138 | L732138 | N-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance PMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75FCCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030139((S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 413nMAssay Description:Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance PMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75FCCPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030124((S)-2-Amino-3-(1H-indol-3-yl)-propionic acid benzy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Affinity to NK3 receptors assayed by displacement of [125I]-Bolton-Hunter labeled eledoisin radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75FCCPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21016(CHEMBL22870 | L 732138 | L-732,138 | L732138 | N-a...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Affinity to NK3 receptors assayed by displacement of [125I]-Bolton-Hunter labeled eledoisin radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75FCCPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030124((S)-2-Amino-3-(1H-indol-3-yl)-propionic acid benzy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to the NK2 receptor assayed by displacement of [125I]-Neurokinin AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75FCCPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030139((S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Affinity to NK3 receptors assayed by displacement of [125I]-Bolton-Hunter labeled eledoisin radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75FCCPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21016(CHEMBL22870 | L 732138 | L-732,138 | L732138 | N-a...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to the NK2 receptor assayed by displacement of [125I]-Neurokinin AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75FCCPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030139((S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to the NK2 receptor assayed by displacement of [125I]-Neurokinin AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75FCCPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030124((S)-2-Amino-3-(1H-indol-3-yl)-propionic acid benzy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance PMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75FCCPubMed
TargetSubstance-P receptor(Rattus norvegicus (rat))
Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21016(CHEMBL22870 | L 732138 | L-732,138 | L732138 | N-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.92E+5nMAssay Description:The inhibitory concentration of the compound against rat neurokinin-1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75FCCPubMed
Displayed 1 to 50 (of 92 total ) | Next | Last >>* indicates data uncertainty>20%