Compile Data Set for Download or QSAR

Found 19 hits of Enzyme Inhibition Constant Data   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128023(CHEMBL3628281)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Negative allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50258140(CHEMBL521982 | N-(4-(trifluoromethyl)oxazol-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50258140(CHEMBL521982 | N-(4-(trifluoromethyl)oxazol-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50258140(CHEMBL521982 | N-(4-(trifluoromethyl)oxazol-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128021(CHEMBL3628116)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50258140(CHEMBL521982 | N-(4-(trifluoromethyl)oxazol-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128021(CHEMBL3628116)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128021(CHEMBL3628116)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128021(CHEMBL3628116)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128232(CHEMBL3628095)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128028(CHEMBL3628088)copy SMILEScopy InChI
Affinity DataEC50:  4.47E+3nMAssay Description:Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128116(CHEMBL3628081)copy SMILEScopy InChI
Affinity DataEC50:  550nMAssay Description:Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128028(CHEMBL3628088)copy SMILEScopy InChI
Affinity DataEC50:  4.47E+3nMAssay Description:Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128116(CHEMBL3628081)copy SMILEScopy InChI
Affinity DataEC50:  550nMAssay Description:Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128232(CHEMBL3628095)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128123(CHEMBL3628106)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128021(CHEMBL3628116)copy SMILEScopy InChI
Affinity DataEC50:  356nMAssay Description:Positive allosteric modulation of rat mGlu1 receptor assessed as potentiation of glutamate-induced calcium mobiliztion by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128021(CHEMBL3628116)copy SMILEScopy InChI
Affinity DataEC50:  390nMAssay Description:Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128123(CHEMBL3628106)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6FQ4PubMed
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