Compile Data Set for Download or QSAR

Found 26 hits of Enzyme Inhibition Constant Data   

TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50177595((2S)-5-amino-2-{[(2S)-1-{[(4R,7S,10S,13S,16R)-13-[...)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178213(4-ethoxy-N-{2-[2-(2-hydroxybenzylidene)hydrazino]-...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178190(CHEMBL200792 | N'-(2-hydroxybenzylidene)-2-(N-(4-c...)copy SMILEScopy InChI
Affinity DataKi:  67nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178212(CHEMBL115305 | N'-(2-hydroxybenzylidene)-2-(N-p-to...)copy SMILEScopy InChI
Affinity DataKi:  67nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178184(CHEMBL200682 | N-(4-chloro-2-methylphenyl)-2-(N-(4...)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Displacement of [125I]LVA antagonist from human vasopressin 1a receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(RAT)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50177595((2S)-5-amino-2-{[(2S)-1-{[(4R,7S,10S,13S,16R)-13-[...)copy SMILEScopy InChI
Affinity DataKi:  76nMAssay Description:Displacement of [125I]OVTA antagonist from rat oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178200(CHEMBL200415 | N-(3-chloro-2-methylphenyl)-2-(N-p-...)copy SMILEScopy InChI
Affinity DataKi:  93nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178214(2-[Benzenesulfonyl-(4-methoxy-phenyl)-amino]-N-(3-...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178176(CHEMBL373167 | N-(2-(3,4-dihydroisoquinolin-2(1H)-...)copy SMILEScopy InChI
Affinity DataKi:  115nMAssay Description:Displacement of [125I]LVA antagonist from human vasopressin 1a receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178174(CHEMBL196974 | N-(3-chloro-2-methylphenyl)-2-(N-(4...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178176(CHEMBL373167 | N-(2-(3,4-dihydroisoquinolin-2(1H)-...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178167(CHEMBL198630 | N'-(1-(2-hydroxyphenyl)ethylidene)-...)copy SMILEScopy InChI
Affinity DataKi:  237nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178214(2-[Benzenesulfonyl-(4-methoxy-phenyl)-amino]-N-(3-...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Displacement of [125I]LVA antagonist from human vasopressin 1a receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178171(CHEMBL381433 | N-(2-(3,4-dihydroisoquinolin-2(1H)-...)copy SMILEScopy InChI
Affinity DataKi:  325nMAssay Description:Displacement of [125I]LVA antagonist from human vasopressin 1a receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178171(CHEMBL381433 | N-(2-(3,4-dihydroisoquinolin-2(1H)-...)copy SMILEScopy InChI
Affinity DataKi:  470nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178189(2-(N-(3-chlorophenyl)phenylsulfonamido)-N'-(1-(2-h...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Displacement of [125I]LVA antagonist from human vasopressin 1a receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178160(CHEMBL198780 | N-(3-chloro-2-methylphenyl)-2-(3,4-...)copy SMILEScopy InChI
Affinity DataKi:  620nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178184(CHEMBL200682 | N-(4-chloro-2-methylphenyl)-2-(N-(4...)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178213(4-ethoxy-N-{2-[2-(2-hydroxybenzylidene)hydrazino]-...)copy SMILEScopy InChI
Affinity DataKi:  3.22E+3nMAssay Description:Displacement of [125I]LVA antagonist from human vasopressin 1a receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178189(2-(N-(3-chlorophenyl)phenylsulfonamido)-N'-(1-(2-h...)copy SMILEScopy InChI
Affinity DataKi:  4.90E+3nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178200(CHEMBL200415 | N-(3-chloro-2-methylphenyl)-2-(N-p-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]LVA antagonist from human vasopressin 1a receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178167(CHEMBL198630 | N'-(1-(2-hydroxyphenyl)ethylidene)-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]LVA antagonist from human vasopressin 1a receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178174(CHEMBL196974 | N-(3-chloro-2-methylphenyl)-2-(N-(4...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]LVA antagonist from human vasopressin 1a receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178179(CHEMBL444879 | N-(3-chloro-2-methylphenyl)-2-(N-(4...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]LVA antagonist from human vasopressin 1a receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178179(CHEMBL444879 | N-(3-chloro-2-methylphenyl)-2-(N-(4...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]OVTA antagonist from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
TargetOxytocin receptor(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50177595((2S)-5-amino-2-{[(2S)-1-{[(4R,7S,10S,13S,16R)-13-[...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibitory activity against human Oxytocin induced intracellular Calcium mobilization in human Oxytocin receptor transfected HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TN3PubMed
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