Found 2 hits of Enzyme Inhibition Constant Data
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
MethylGene Inc.
Curated by ChEMBL
MethylGene Inc.
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
MethylGene Inc.
Curated by ChEMBL
MethylGene Inc.
Curated by ChEMBL
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT2 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair