Compile Data Set for Download or QSAR

Found 21 hits of Enzyme Inhibition Constant Data   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Antiproliferative activity against PDGF-BB stimulated HCASMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against PDGFRbeta kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against c-ABLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against LCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Inhibitory activity against c-SRCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 378nMAssay Description:Inhibitory activity against FYNMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity against VEGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetCasein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory activity against Casein Kinase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against HER2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory activity against GSK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibitory activity against bFGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 5.67E+4nMAssay Description:Inhibitory activity against CDK7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against CDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against FAKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against MAPKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against PKAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against IRKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against CDK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179207(3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095HWPubMed
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