Compile Data Set for Download or QSAR

Found 8 hits of Enzyme Inhibition Constant Data   

LigandPNGBDBM50187114(CHEMBL3823303)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal His-tagged human TAK1 (1 to 303 amino acids)/human TAB1 (437 to 504 amino acids) expressed in baculovirus expression system ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C2FPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50187114(CHEMBL3823303)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant FLAG-tagged TAK1 (unknown origin) co-expressed with TAB (unknown origin) in baculovirus using BT-MKK as substrate after 1 h...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C2FPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50187114(CHEMBL3823303)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant FLAG-tagged TAK1 (unknown origin) co-expressed with TAB (unknown origin) in baculovirus using BT-MKK as substrate after 1 h...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C2FPubMed
LigandPNGBDBM50187114(CHEMBL3823303)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal His-tagged human TAK1 (1 to 303 amino acids)/human TAB1 (437 to 504 amino acids) expressed in baculovirus expression system ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C2FPubMed
LigandPNGBDBM50042034((5Z)-7-Oxozeaenol | 5Z-7-Oxozeaenol | CHEBI:67559 ...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of full length TAK1/TAB1 (unknown origin) using biotin-MKK6 as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
LigandPNGBDBM50042034((5Z)-7-Oxozeaenol | 5Z-7-Oxozeaenol | CHEBI:67559 ...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of full length TAK1/TAB1 (unknown origin) using biotin-MKK6 as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50187115(CHEMBL3822835)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C2FPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50187115(CHEMBL3822835)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C2FPubMed
* indicates data uncertainty>20%