Compile Data Set for Download or QSAR

Found 12 hits of Enzyme Inhibition Constant Data   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50163592((3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-met...)copy SMILEScopy InChI
Affinity DataIC50: 1.21nMAssay Description:Antagonist activity at human mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50212324(6-amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-alph...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50212322(4-methoxyphenyl-6-methoxyquinazolin-4-yl | CHEMBL2...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50212323((3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-h...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50212325((S)-(ALPHA)-METHYL-4-CARBOXYPHENYLGLYCINE | (S)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50212325((S)-(ALPHA)-METHYL-4-CARBOXYPHENYLGLYCINE | (S)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at mGlu2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50053588((S)-4-(amino(carboxy)methyl)benzoic acid | (S)-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50052256((S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50053586((S)-3-Carboxy-4-hydroxyphenylglycine | (S)-5-(amin...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50053585((S)-4-(amino(carboxy)methyl)-2-hydroxybenzoic acid...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50400856(CHEMBL2021372)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+5nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Lilly Research Labs

Curated by ChEMBL
LigandPNGBDBM50053585((S)-4-(amino(carboxy)methyl)-2-hydroxybenzoic acid...)copy SMILEScopy InChI
Affinity DataEC50:  4.80E+4nMAssay Description:Agonist activity at mGlu2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5W7QPubMed
* indicates data uncertainty>20%