Affinity Data by PubMed id=24656661

Found 1 hit of Enzyme Inhibition Constant Data

E3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50229787((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...)copy SMILEScopy InChI

IC50: 70nMAssay Description:Binding affinity to HDM2 (unknown origin) by fluorescence polarization peptide displacement assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase CHEMBL MCE
PC cid PC sid PDB Patents Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2XD136FPubMed PDB

3D Structure (crystal)

* indicates data uncertainty>20%