Compile Data Set for Download or QSAR

Found 8 hits of Enzyme Inhibition Constant Data   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RQ7PubMedDrugBank
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Displacement of [3H]paroxetine from SERT in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RQ7PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RQ7PubMedDrugBank
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)copy SMILEScopy InChI
Affinity DataIC50: 72.4nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RQ7PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)copy SMILEScopy InChI
Affinity DataIC50: 93.8nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RQ7PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50243895(1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane ...)copy SMILEScopy InChI
Affinity DataIC50: 215nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RQ7PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataIC50: 581nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RQ7PubMedDrugBank
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)copy SMILEScopy InChI
Affinity DataIC50: 7.34E+3nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RQ7PubMedDrugBank
* indicates data uncertainty>20%