Compile Data Set for Download or QSAR

Found 6 hits of Enzyme Inhibition Constant Data   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287558(CHEMBL1333494)copy SMILEScopy InChI
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287521(CHEMBL2146753)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287521(CHEMBL2146753)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287521(CHEMBL2146753)copy SMILEScopy InChI
Affinity DataIC50: 744nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287521(CHEMBL2146753)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50287558(CHEMBL1333494)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0QVZPubMed
* indicates data uncertainty>20%