Compile Data Set for Download or QSAR

Found 8 hits of Enzyme Inhibition Constant Data   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50296742(1,4-diazabicyclo[3.2.2]nonane-(4-bromo)-phenyl car...)copy SMILEScopy InChI
Affinity DataKi:  38nMAssay Description:Displacement of [125I]BTX from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0N69PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50296735(CHEMBL552931 | N-(4-bromophenyl)-1,4-diazabicyclo[...)copy SMILEScopy InChI
Affinity DataKi:  328nMAssay Description:Displacement of [125I]BTX from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0N69PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50296731(4-(4-bromophenylsulfonyl)-1,4-diazabicyclo[3.2.2]n...)copy SMILEScopy InChI
Affinity DataKi: >4.72E+3nMAssay Description:Displacement of [125I]BTX from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0N69PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataIC50: 1.65nMAssay Description:Displacement of L-[3H]Nicotine from alpha4beta2 nAChR in rat brain homogenate by rapid filtration methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50329578((-)-9-Bromocytisine | (1R,5S)-9-Bromo-1,2,3,4,5,6-...)copy SMILEScopy InChI
Affinity DataIC50: 15.6nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0N69PubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50296742(1,4-diazabicyclo[3.2.2]nonane-(4-bromo)-phenyl car...)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of [3H]LY278584 from human 5HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0N69PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50296742(1,4-diazabicyclo[3.2.2]nonane-(4-bromo)-phenyl car...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of L-[3H]Nicotine from alpha4beta2 nAChR in rat brain homogenate by rapid filtration methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0N69PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50296742(1,4-diazabicyclo[3.2.2]nonane-(4-bromo)-phenyl car...)copy SMILEScopy InChI
Affinity DataIC50: 6.48E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0N69PubMed
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