Compile Data Set for Download or QSAR

Found 10 hits of Enzyme Inhibition Constant Data   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505859(CHEMBL4436748)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of full-length human C-terminal NanoLuc-tagged P38 alpha MAPK expressed in human HEK293T cells incubated for 2 hrs followed by NanoBRET Na...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505859(CHEMBL4436748)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505859(CHEMBL4436748)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of p38-beta (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NJKPubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505859(CHEMBL4436748)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human His-tagged P38beta MAPK (1 to 364 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP bas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NJKPubMed
TargetMitogen-activated protein kinase kinase kinase 2(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505859(CHEMBL4436748)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:Inhibition of ZAK (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NJKPubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505859(CHEMBL4436748)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of DDR1 (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NJKPubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505859(CHEMBL4436748)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of DDR2 (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NJKPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505859(CHEMBL4436748)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of KIT (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NJKPubMed
TargetMyosin light chain kinase family member 4(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505859(CHEMBL4436748)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MYLK4 (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate addition by NanoBRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NJKPubMed
TargetRibosomal protein S6 kinase alpha-6(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50505859(CHEMBL4436748)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of RSK4 kinase domain 1 (unknown origin) expressed in human HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate additi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NJKPubMed
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